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What is Menopause?

Menopause Symptoms

About PREMPRO

Benefits of PREMPRO

Taking PREMPRO

Safety and Side Effects

Talking With Your Doctor

Menopause Resources

Glossary

Ask your doctor how PREMPRO can help relieve your hot flashes, night sweats, and vaginal symptoms.

Only experiencing vaginal symptoms from menopause? Learn about a prescription cream that may help.

View the patient information Access the most current Patient Information, Including Boxed Warning for PREMPRO

Patient Information, Including Boxed Warning • Important Safety Information • Full Prescribing Information

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Important Safety Information

What is the most important information I should know about PREMPRO and PREMPHASE (combinations of estrogens and a progestin)?

Do not use estrogens with progestins to prevent heart disease, heart attacks, strokes, or dementia (decline of brain function)
Using estrogens with progestins may increase your chances of getting heart attacks, strokes, breast cancer, or blood clots
Using estrogens with progestins may increase your chance of getting dementia, based on a study of women age 65 years or older
Do not use estrogen-alone to prevent heart disease, heart attacks, or dementia
Using estrogen-alone may increase your chance of getting cancer of the uterus (womb)
Using estrogen-alone may increase your chances of getting strokes or blood clots
Using estrogen-alone may increase your chance of getting dementia, based on a study of women age 65 years or older
You and your healthcare provider should talk regularly about whether you still need treatment with PREMPRO or PREMPHASE

If you use or are considering PREMPRO only to treat your menopausal changes in or around your vagina, talk with your healthcare provider about whether a topical vaginal product would be better for you.

If you use or are considering PREMPRO only to prevent osteoporosis due to menopause, talk with your healthcare provider about whether a different treatment or medicine without estrogens would be better for you.

Do not take PREMPRO if you have unusual vaginal bleeding; currently have or have had cancer of the breast or uterus; had a stroke or heart attack; currently have or have had blood clots; currently have or have had liver problems; have had a bleeding disorder; are allergic to PREMPRO or any of their ingredients; or think you may be pregnant.

In a clinical trial, the most common side effects (>5%) that occurred with PREMPRO were vaginal bleeding, vaginitis due to yeast or other causes, painful menstruation, breast enlargement, breast pain, and leg cramps.

PREMPRO (conjugated estrogens/medroxyprogesterone acetate tablets) is a prescription treatment used after menopause. PREMPRO is used after menopause to reduce moderate to severe hot flashes, to treat menopausal changes in and around the vagina, and to help reduce your chances of getting osteoporosis (thin, weak bones).

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The health information contained herein is provided for educational purposes only and is not intended to replace discussions with a healthcare provider. All decisions regarding patient care must be made with a healthcare provider, considering the unique characteristics of the patient.

The product information provided in this site is intended for residents of the United States. The products discussed herein may have different product labeling in different countries.

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