Benefits of PREMPRO

PREMPRO relieves the symptoms of menopause.

Low doses of PREMPRO, such as 0.3 mg/1.5 mg and 0.45 mg/1.5 mg, have been proven to effectively relieve moderate to severe hot flashes, night sweats, and vaginal symptoms. These options allow your healthcare professional to choose the option that is right for you.

  • You may start to feel relief from hot flashes in as little as 2 to 3 weeks.
  • Hot flashes and night sweats are likely to become less frequent and less intense.

If your symptoms of menopause are only vaginal symptoms such as dryness, burning, and itching in and around vagina, ask your doctor about vaginal estrogen cream.

PREMPRO helps prevent osteoporosis.

Postmenopausal women are especially susceptible to fractures of the hip, wrist, and spine. PREMPRO can help reduce your chances of developing osteoporosis because it has been shown to increase bone mineral density at the hip and spine and help prevent postmenopausal osteoporosis.

If you do not have menopausal symptoms such as hot flashes and night sweats, non-estrogen treatments should be carefully considered before taking PREMPRO solely for the prevention of postmenopausal osteoporosis.

PREMPRO offers low dose options.

PREMPRO offers low dose options for the shortest duration consistent with your treatment goals and risks.

PREMPRO comes in several dosage strengths-including two low dose formulations. These options allow your healthcare professional to choose the one that is right for you.

You should see your doctor regularly during therapy to review your treatment plan.

Ask your doctor about PREMPRO at your next visit.  Learn more

Scroll for Important Safety Information and Indication

Do not use estrogens, with or without progestins, to prevent heart disease, heart attacks, strokes or dementia (decline in brain function). Using estrogens, with or without progestins, may increase your chance of getting dementia, based on a study of women 65 years of age or older.

Using estrogens with progestins may increase your chances of getting heart attacks, strokes, breast cancer, or blood clots.

You and your healthcare provider should talk regularly about whether you still need treatment with PREMPRO.

PREMPRO should not be used if you have unusual vaginal bleeding; have or had cancer; had a stroke or heart attack; have or had blood clots or liver problems; have a bleeding disorder; are allergic to any of its ingredients; or think you may be pregnant.

In a clinical trial, the most common side effects (>5%) that occurred with PREMPRO were vaginal bleeding, vaginitis due to yeast or other causes, painful menstruation, breast enlargement, breast pain, and leg cramps.

INDICATIONS
PREMPRO is used after menopause to reduce moderate to severe hot flashes; to treat moderate to severe dryness, itching, and burning, in and around the vagina; and to help reduce the chances of getting osteoporosis (thin weak bones).

If you are using or are considering using PREMPRO only to treat symptoms of vaginal dryness, consider topical therapies first. If you are using or are considering using PREMPRO only to prevent osteoporosis due to menopause, talk with your health care professional about whether a different treatment or medicine without estrogens might be better for you. PREMPRO should be used at the lowest effective dose and for the shortest duration consistent with your treatment goals and risks.


Please see Full Prescribing Information including Boxed Warning and Patient Information.